A patient-centric healthcare company focusing on therapies designed for testosterone deficiency
Marius Pharmaceuticals is paving the way for a new frontier in testosterone. We believe that testosterone is central to overall health and wellbeing, which is why we have spent more than a decade developing a proprietary oral testosterone therapy to help the millions suffering from the unwanted symptoms of testosterone deficiency.
The crucial role that testosterone plays in the human body has been neglected for far too long with patients bearing the consequences. Aside from its well-known role as the “sex hormone,” testosterone is essential to many bodily functions...
Testosterone may play an important role in brain health and cognitive function, with low levels causing issues with memory, clarity, and concentration. Mood disorders, like anxiety and depression, can be exacerbated by low testosterone levels.
Muscle development, fat metabolism, and bone strength are all dependent on testosterone. Testosterone is key in stimulating muscle tissue growth, increasing bone density and by controlling metabolic efficiency, the hormone indirectly decreases body fat and glucose concentrations.
Many studies have shown that testosterone is actually cardioprotective and is key in regulating blood flow, inflammation, and vascular function.
The hormone serves a meaningful role in sex drive and performance. When levels are too low, individuals may experience low libido and erectile dysfunction.
Evidence supports the need for research initiatives to examine hormone imbalance within other comorbidities and patient populations.
Obesity and low testosterone levels are closely related with numerous studies having established an inverse relationship between the two. Studies have shown that long-term testosterone therapy in men with testosterone deficiency produces significant weight loss, notable reduction in waist circumference and BMI, and improvements in body composition.1
Testosterone therapy has shown promising success in individuals with type 2 diabetes. T4DM was a randomized, double-blind, placebo-controlled, 2-year phase 3B trial that examined the effects of testosterone therapy in men with type 2 diabetes. One-third of the men treated with testosterone saw remission of their diabetes. The testosterone group saw greater decrease in waist circumference, total and abdominal fat mass, and fasting glucose. The magnitude of effect of testosterone to prevent type 2 diabetes was greater than that seen for metformin in the Diabetes Prevention Program.2
The benefits of testosterone therapy are not limited to just men. The potential uses of testosterone therapy for women are becoming increasingly evident. For example, testosterone reduces the symptoms of menopause and poses no major adverse side effects. Healthy young women have up to 20x more testosterone than estrogen.3
Base Healthcare is a purpose-built, specialty clinic focusing on Adequate Testosterone Therapy™ and foundational health.
Base Healthcare is a subsidiary of Marius Pharmaceuticals.
We’re a growing team of innovative trailblazers and thought leaders.
With over 100 years of combined experience, we’ve got a well-seasoned team at the wheel.
We’re looking for people who love to think outside of the box, solve complex issues, and work alongside an enthusiastic team of movers and shakers.Join Us
KYZATREX™ (testosterone undecanoate) is a prescription drug that is used to treat adult men who have low or no testosterone levels due to certain medical conditions.
KYZATREX™ is a controlled substance (CIII) because it contains testosterone. It is not known if KYZATREX™ is safe or effective in males younger than 18 years old. Improper use may affect bone growth in children. KYZATREX™ is not meant for use by women.
KYZATREX™ can increase blood pressure, which can increase the risk of having a heart attack or stroke and can increase risk of death due to a heart attack or stroke. Your risk may be greater if you have already had a heart attack or stroke or if you have other risk factors for heart attack or stroke.
Do not take KYZATREX™ if you: have breast cancer; have or might have prostate cancer; are a woman who is pregnant (KYZATREX™ may harm your unborn baby); are allergic to KYZATREX™ or any of its ingredients; or have low testosterone without certain medical conditions (e.g., do not take KYZATREX™ if you have low testosterone due to age).
Before you take KYZATREX™, tell your healthcare provider about all of your medical conditions, including if you: have high blood pressure or are treated for high blood pressure; have a history of diabetes; have heart problems; have high red blood cell count (hematocrit) or high hemoglobin laboratory value; have urinary problems due to an enlarged prostate; have liver or kidney problems; or have problems breathing while you sleep (sleep apnea).
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Taking KYZATREX™ with certain other medicines can affect each other. Especially, tell your healthcare provider if you take: insulin; medicines that decrease blood clotting (blood thinners); corticosteroids; or medicines that increase blood pressure, such as some cold medicine and pain medicines.
Call your healthcare provider right away if you have any of the serious side effects listed above.
The most common side effect of KYZATREX™ is high blood pressure. Other side effects may include: headache, joint or back pain, diarrhea, increased red blood cell count, anxiety, constipation, swelling of the legs, and increased prostate specific antigen (PSA) levels.
These are not all the possible side effects of KYZATREX™. For more information, ask your healthcare provider or pharmacist.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088. You may also report side effects to Marius by visiting www.mariuspharma.com.
Keep KYZATREX™ and all medicines out of the reach of children.